eucalyptus oil inhalation toxicity

• Sensitization at maximum concentration of use (i.e., Eucalyptus Globulus Leaf Oil at 5.5%) • Impurity data on all ingredients • Margin of safety (MOS) calculations for inhalation and dermal exposure using the Eucalyptus Globulus Leaf Oil and/or the major constituent, eucalyptol (1,8 -cineole) Eucalyptus oil is also safe to use at about 1% in a chest rub for small children. Eucalyptus oil is the generic name for distilled oil from the leaf of Eucalyptus, a genus of the plant family Myrtaceae native to Australia and cultivated worldwide. Eucalyptus oil should never be taken orally, except under the guidance of a qualified physician. Children are particularly susceptible. The severity of toxicity is dependent on the type of oil and the amount ingested. Liver and kidney damage was found in laboratory animals repeatedly given by mouth nonlethal doses of 1,8-cineole or eucalyptus oil. On the other hand, applying undiluted eucalyptus oil to the face – or even to the feet – of an infant would be unwise and risky. As little as 2mL (less than half a teaspoon) of eucalyptus oil can cause significant poisoning in an infant. Eucalyptus oil has been used in different medications to relieve symptoms of asthma and rhinitis and is a constituent of cold remedies and ointments designed to be rubbed on to the chest or applied around and even into the nostrils (Vicks Vaporub, Obat Madjan, etc.). Eucalyptus Organic Essential Oil Irritating to skin. Toxicity. To compare the effects of oral therapy with Cineol (3 x 200 mg/day), a monoterpene of eucalyptus oil, and Ambroxol (3 x 30 mg/day) after a treatment over … Diluted eucalyptus oil may also be applied to the skin as a remedy for health problems such … Eucalyptus species. Eucalpytus oil is extracted from the leaves of the tree. Taking just a few millilitres can result in stomach pains, nausea, and in some cases, even convulsions. • Sensitization on Eucalyptus Globulus Leaf Oil at 5.5% or greater • Impurity data on all ingredients • Margin of safety (MOS) calculations for inhalation and dermal exposure using the Eucalyptus Globulus Leaf Oil and/or the major constituent, eucalyptol (1,8-cineole) But the researchers found just under half of the calls made to the centre were for eucalyptus essential oils. Pharmacokinetics: Essential oil concentrations range from 1-20% and volumes of 5-15 mL are likely to cause some degree of toxicity. STOT-single exposure Not Classified. Deaths occurred in laboratory animals given single high doses of 1,8-cineole or eucalyptus oil by mouth. Applied to the skin it acts as a rubefacient and counterirritant, but substantial concentrations of … Some deaths occurred in people swallowing as little as a teaspoon of eucalyptus oil. Carcinogenicity Not Classified Reproductive toxicity No toxicity to reproduction. Eucalyptus taken by mouth can interfere with the absorption of drugs that are metabolized by the liver. Eucalyptus is a tree that is native to Australia. Eucalyptus oil is available as an essential oil that is used as a medicine to treat a variety of common diseases and conditions including nasal congestion, asthma, and as a tick repellant. There are two reports of serious adverse reactions by children to non-oral eucalyptus oil – ages 4 and 6 (EOS page 274). The National Institutes of Health warn that relatively small amounts of eucalyptus oil can cause a fatal overdose. Eucalyptus oil has a history of wide application, as a pharmaceutical, antiseptic, repellent, flavouring, fragrance and industrial uses. Significant toxicity has been reported following topical administration of eucalyptus oil containing 80% eucalyptol 3 PEDIATRIC TIP: alterations in mental status can present with ingestion of as little as 2-3 mL and significant depression of consciousness should be expected with > 5 mL ingestion of 100% eucalyptus oil 5 , 7 Respiratory or skin sensitization May cause an allergic skin reaction Germ cell mutagenicity No mutagenic effects. The leaves of selected Eucalyptus species are steam distilled to extract eucalyptus oil. Deaths from essential oil … Serious eye damage/irritation Causes eye irritation. Symptoms of toxicity include: drowsiness, slow/shallow breathing, coma (after large ingestion) seizures For eucalyptus oil ingestions see the separate Eucalyptus oil Poisoning guideline.

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